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1.
Ksii Transactions on Internet and Information Systems ; 16(4):1128-1145, 2022.
Article in English | Web of Science | ID: covidwho-1869887

ABSTRACT

Owing to the rapid development of information science, data analysis based on machine learning has become an interdisciplinary and strategic area. Marine predators algorithm (MPA) is a novel metaheuristic algorithm inspired by the foraging strategies of marine organisms. Considering the randomness of these strategies, an improved algorithm called co-evolutionary cultural mechanism-based marine predators algorithm (CECMPA) is proposed. Through this mechanism, search agents in different spaces can share knowledge and experience to improve the performance of the native algorithm. More specifically, CECMPA has a higher probability of avoiding local optimum and can search the global optimum quickly. In this paper, it is the first to use CECMPA to perform feature subset selection and optimize hyperparameters in support vector machine (SVM) simultaneously. For performance evaluation the proposed method, it is tested on twelve datasets from the university of California Irvine (UCI) repository. Moreover, the coronavirus disease 2019 (COVID-19) can be a real-world application and is spreading in many countries. CECMPA is also applied to a COVID-19 dataset. The experimental results and statistical analysis demonstrate that CECMPA is superior to other compared methods in the literature in terms of several evaluation metrics. The proposed method has strong competitive abilities and promising prospects.

2.
Green Chemistry ; : 7, 2021.
Article in English | Web of Science | ID: covidwho-1356588

ABSTRACT

Quaternary ammonium compounds (QACs) are a class of cationic surfactants routinely used for the disinfection of industries, institutions and households, and have seen a sharp increase in use during the COVID-19 pandemic. However, current commercial QACs consist of only stable chemical bonds such as C-N, C-C, and C-H, which makes their natural degradation rather difficult. Recent studies suggest that emerging negative environmental impacts, such as systemic antibiotics resistance and toxicity to living organisms, are directly associated with prolonged exposure to QACs. Here we report a new class of QAC which contains relatively volatile chemical functional groups such as ester and thioether bonds. Degradation kinetics in aqueous solutions suggests that the stability of these QACs depends not only on their intrinsic hydrophobicity but also on external environmental factors such as pH, temperature and ion presence. The microbicidal effects of QACs containing carbon chains with various lengths were also tested, one of which, named "Ephemora", is highly active against a broad spectrum of microbes including fungi, bacteria and viruses, for instance, methicillin-resistant Staphylococcus aureus (MRSA). The easy synthesis and purification of Ephemora starting from inexpensive commercially available reagents, together with its excellent antimicrobial activity and ability to degrade in natural waters over time, make its large-scale commercial production possible.

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